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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPTAN1 All Species: 36.97
Human Site: T2425 Identified Species: 73.94
UniProt: Q13813 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13813 NP_001123910.1 2472 284539 T2425 S E G K P Y V T K E E L Y Q N
Chimpanzee Pan troglodytes XP_001169918 2416 279460 K2370 E G K S Y I T K E D M K Q A L
Rhesus Macaque Macaca mulatta XP_001117106 2440 281752 K2393 E G K S Y I T K E D M K Q A L
Dog Lupus familis XP_537823 2573 295678 T2526 S E G K P Y V T K E E L Y Q N
Cat Felis silvestris
Mouse Mus musculus P16546 2472 284579 T2425 S E G K P Y V T K E E L Y Q N
Rat Rattus norvegicus P16086 2472 284619 T2425 S E G K P Y V T K E E L Y Q N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P07751 2477 285345 T2430 S E R K P Y V T K E E L Y Q N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001091958 2480 284939 T2433 A E N K P Y V T K E E L Y Q N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13395 2415 278284 T2367 A A D R P Y V T K E E L Y C N
Honey Bee Apis mellifera XP_623691 2418 278393 T2370 A A D R P Y V T K E E L Y A N
Nematode Worm Caenorhab. elegans NP_508537 2427 281735 T2379 K E F R P Y V T A E E L Y A N
Sea Urchin Strong. purpuratus XP_785949 2410 278516 T2363 A E G K P Y V T K Q E L Y A N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 55.7 56.5 94.6 N.A. 98.4 98.5 N.A. N.A. 96.1 N.A. 90 N.A. 64.5 66.1 58.5 63
Protein Similarity: 100 72.9 73.5 95.6 N.A. 99.2 99.3 N.A. N.A. 98.3 N.A. 94.8 N.A. 78.9 79.6 75.1 77.5
P-Site Identity: 100 0 0 100 N.A. 100 100 N.A. N.A. 93.3 N.A. 86.6 N.A. 66.6 66.6 66.6 80
P-Site Similarity: 100 13.3 13.3 100 N.A. 100 100 N.A. N.A. 93.3 N.A. 93.3 N.A. 80 80 73.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 17 0 0 0 0 0 0 9 0 0 0 0 42 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 0 0 17 0 0 0 0 0 0 17 0 0 0 0 0 % D
% Glu: 17 67 0 0 0 0 0 0 17 75 84 0 0 0 0 % E
% Phe: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 17 42 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 17 59 0 0 0 17 75 0 0 17 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 84 0 0 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 84 % N
% Pro: 0 0 0 0 84 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 9 0 0 17 50 0 % Q
% Arg: 0 0 9 25 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 42 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 17 84 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 84 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 17 84 0 0 0 0 0 0 84 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _